岡山理科大学獣医学部

研究・教員紹介

HOME研究・教員紹介実験動物管理講座(Laboratory Animal Science and Technology)小野 文子

小野 文子准教授

学位
博士(農学)
https://researchmap.jp/ninchan3243/

専門分野

人獣共通感染症

脳神経疾患

サル

研究分野

人獣共通感染症

プリオン病

霊長類医科学研究 

研究内容

プリオン病の治療研究
野生動物保有病原性大腸菌の検索
愛玩動物における薬剤耐性菌に関する調査研究

研究業績

  1. Yamaguchi K, Kamatari YO, Ono F, Shibata H, Fuse T, Elhelaly AE, Fukuoka M, Kimura T, Hosokawa-Muto J, Ishikawa T, Tobiume M, Takeuchi Y, Matsuyama Y, Ishibashi D, Nishida N, Kuwata K, A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques. Nature biomedical engineering. 2019. 3(3) 206-219
  2.  Sehara Y, Fujimoto KI, Ikeguchi K, Katakai Y, Ono F, Takino N, Ito M, Ozawa K, Muramatsu SI. Persistent Expression of Dopamine-Synthesizing Enzymes 15 Years After Gene Transfer in a Primate Model of Parkinson’s Disease. Human gene therapy. 2017. Clinical development 28(2) 74-79
  3. Hara H, Ono F, Nakamura S, Matsumoto SE, Jin H, Hattori N, Tabira T.
    An Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in Aged Monkeys: Reduction in Plaque Amyloid and Increase in Aβ Oligomers. Journal of Alzheimer’s disease : JAD. 2016. 54(3) 1047-1059
  4.  Uchida A, Sasaguri H, Kimura N, Tajiri M, Ohkubo T, Ono F, Sakaue F, Kanai K, Hirai T, Sano T, Shibuya K, Kobayashi M, Yamamoto M, Yokota S, Kubodera T, Tomori M, Sakaki K, Enomoto M, Hirai Y, Kumagai J, Yasutomi Y, Mochizuki H, Kuwabara S, Uchihara T, Mizusawa H, Yokota T. Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43. Brain. 2012, 135, (3) 833–846,
  5.  Ono F, Terao K, Tase N, Hiyaoka A, Ohyama A, Tezuka Y, Wada N, Kurosawa A, Sato Y, Tobiume M, Hagiwara K, Yamakawa Y, Sata T Experimental transmission of bovine spongiform encephalopathy (BSE) to cynomolgus macaques, a non-human primate. Japanese journal of infectious diseases. 2011. 64(1) 50-54
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