岡山理科大学獣医学部

研究・教員紹介

HOME研究・教員紹介村上 康平

村上 康平助教

学位
博士(獣医学)
Research map: http://researchmap.jp/Kohei_Murakami/
ORCID: https://orcid.org/0000-0001-5458-410X
Google Scholar Citations: https://scholar.google.com/citations?user=laNb9KEAAAAJ&hl=ja&oi=ao

専門分野

免疫学

研究分野

・犬の多発性関節炎
・骨代謝
・免疫グロブリンの糖鎖修飾

研究内容

 ・犬の多発性関節炎の病態解明
 ・骨代謝におけるWNTシグナルの機能解析
 ・犬/猫における糖鎖修飾された免疫グロブリンの機能解析

 

犬の関節リウマチの外観

WNTシグナルの概略図 

IgGの糖鎖修飾

 

研究業績

  1. K. Murakami, H. Nakagawa, K. Nishimura, S. Matsuo. Changes in peptidergic fiber density in the synovium of mice with collagenase-induced acute arthritis. Can J Physiol Pharmacol, 93, 435–441, 2015
  2. K. Murakami, T. Yonezawa, N. Matsuki. Synovial fluid total protein concentration as a possible marker for canine idiopathic polyarthritis. J Vet Med Sci, 77, 1715–1717, 2015
  3. K. Murakami, S. Maeda, T. Yonezawa, N. Matsuki. Synovial fluid matrix metalloproteinase-2 and -9 activities in dogs suffering from joint disorders. J Vet Med Sci, 78, 1051–1054, 2016
  4. K. Murakami, S. Maeda, T. Yonezawa, N. Matsuki. CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis. Vet Immunol Immunopathol, 182, 52–58, 2016
  5. K. Murakami, Y. Kobayashi, S. Uehara, T. Suzuki, M. Koide, T. Yamashita, M. Nakamura, N. Takahashi, H. Kato, N. Udagawa, Y. Nakamura. A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro. PLoS ONE, 12, e0181126, 2017
  6. K. Murakami, S. Kikugawa, Y. Kobayashi, S. Uehara, T. Suzuki, H. Kato, N. Udagawa, Y. Nakamura. Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts. Biochem Biophys Res Commun, 505, 419–425, 2018
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