宮前　二朗助教

博士（獣医学）
Researchmap: https://researchmap.jp/jiro_miyamae/

比較免疫学

主要組織適合性複合体（Major histocompatibility complex: MHC）

研究テーマ

• 動物MHC遺伝子群の多型解析
• MHC多型と疾患関連解析
• イヌおよびネコのがんワクチン開発

1. 宮前二朗、岡野雅春、片倉文彦、森友忠昭、椎名 隆, イヌMHC遺伝子群の多型性と犬種内および犬種間におけるDLAハプロタイプの多様性の特徴, Major Histocompatibility Complex, 31(1), 29-40, 2024.
2. Jiro Miyamae, Masaharu Okano, Fumihiko Katakura, Jerzy K. Kulski, Tadaaki Moritomo, Takashi Shiina, Large-Scale Polymorphism Analysis of Dog Leukocyte Antigen Class I and Class II Genes (DLA-88, DLA-12/88L and DLA-DRB1) and Comparison of the Haplotype Diversity between Breeds in Japan, Cells,12(5):809, 2023.
3. Jiro Miyamae, Masaharu Okano, Kohei Nishiya, Fumihiko Katakura, Jerzy K. Kulski, Tadaaki Moritomo, Takashi Shiina, Haplotype structures and polymorphisms of dog leukocyte antigen (DLA) class I shaped by intralocus and interlocus recombination events, Immunogenetics, 74, 245-259. 2022.
4. Keita Sato*, Jiro Miyamae*, Manabu Sakai, Masahru Okano, Fumihiko Katakura, Hisashi Shibuya, Tomohiro Nakayama, Tadaaki Moritomo. *These authors contributed equally to this work. The utility of DLA typing for transplantation medicine in canine models, Journal of veterinary medical science. 82(8), 2020.
5. Jiro Miyamae, Hayato Yagi, Keita Sato, Masaharu Okano, Kohei Nishiya, Fumihiko Katakura, Manabu Sakai, Tomohiro Nakayama, Tadaaki Moritomo, Takashi Shiina. Evaluation of allo-reactive T cells based on the degree of MHC incompatibility using flow cytometric mixed lymphocyte reaction assay in dogs, Immunogenetics. 71(10):635-645, 2019.
6. Jiro Miyamae, Shingo Suzuki, Fumihiko Katakura, Sae Uno, Mizuki Tanaka, Masaharu Okano, Taro Matsumoto, Jerzy K. Kulski, Tadaaki Moritomo, Takashi Shiina, Identification of novel polymorphisms and two distinct haplotype structures in dog leukocyte antigen class I genes: DLA-88, DLA-12 and DLA-64, Immunogenetics. 70, 237-255, 2018.
7. 宮前二朗,　宇野沙恵,　田中瑞樹,　片倉文彦,　難波信一,　坂井学,　亘敏広,　鈴木進悟,　椎名隆, イヌMHCクラスIおよびクラスII遺伝子座の多型解析とハプロタイプの推定, 日本DNA多型学会・DNA多型、24(1), 81-86, 2016.