西木　禎一教授

博士(農学)

research map：https://researchmap.jp/tnishiki

シナプス伝達、開口放出、カルシウムイオン、神経伝達物質

• 神経伝達物質の開口放出機構の解明

• 神経ペプチドが中枢神経系に及ぼす影響の解析

• 神経毒性物質の作用機序の解明

1. Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons. Latt HM, Matsushita H, Morino M, Koga Y, Michiue H, Nishiki T, Tomizawa K, Matsui H. Neuroscience. (2018) 379:383–389.
2. Ca2+-independent syntaxin binding to the C2B effector region of synaptotagmin.
   Masumoto T, Suzuki K, Ohmori I, Michiue H, Tomizawa K, Fujimura A, Nishiki T, Matsui H. Mol Cell Neurosci. (2012) 49:1–8.
3. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Burgalossi A, Jung S, Meyer G, Jockusch WJ, Jahn O, Taschenberger H, O’Connor VM, Nishiki T, Takahashi M, Brose N, Rhee JS. Neuron. (2010) 68:473–487.
4. Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release. Nishiki T, Augustine GJ. J Neurosci. (2004) 24:8542–8550.
5. Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes. Nishiki T, Kamata Y, Nemoto Y, Omori A, Ito T, Takahashi M, Kozaki S. J Biol Chem. (1994) 269:10498–10503.