学位
専門分野
獣医薬理学
研究分野
薬理学
血管生物学
循環器学
分子生物学
遺伝学
研究内容
・高血圧症の発生及び分子メカニズムの解明
・糖尿病性血管障害の分子メカニズムの解明
研究業績
- Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD. RhoBTB1 Protects Against Hypertension and Arterial Stiffness by Restraining Phosphodiesterase 5 Activity. J Clin Invest. in press.
- Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD. A Hypertension-causing Mutation in PPARγ Impairs its Anti-inflammatory Action in Vascular Smooth Muscle. Hypertension. 70(1): 174-182, 2017.
- Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD. Endothelial PPARγ Provides Vascular Protection from IL-1β-Induced Oxidative Stress. Am J Physiol Heart Circ Physiol. 310(1): H39-48, 2016. APSselect（米国生理学会注目論文）に選出
- Mukohda M, Morita T, Okada M, Hara Y, Yamawaki H. Long-term methylglyoxal treatment causes endothelial dysfunction of rat isolated mesenteric artery. J Vet Med Sci. 75(2); 151-157, 2013.
- Mukohda M, Morita T, Okada M, Hara Y, Yamawaki H. Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery. Pharmacol Res. 65(1): 91-9, 2012.
