作道　章一教授

学位

博士（農学）
researchgate https://www.researchgate.net/profile/Akikazu_Sakudo
researchmap: https://researchmap.jp/sakudo/

専門分野

食品衛生学、ウイルス学

研究分野

プリオン、ウイルス、食品衛生、殺菌、滅菌

研究内容

プリオンと食中毒関連ウイルスの感染病態機構の解明
プリオンと食中毒関連ウイルスの不活化技術の開発
殺菌滅菌装置の開発（プラズマ技術を用いた農産物殺菌装置など）
食品検査装置の開発（近赤外分光法など）

研究業績

  1. Yagyu Y, Sakudo A*. Water Plasma Generated from In-Situ Adsorbent-Released Vapor Inactivates Bacterial Spores and Damages DNA and Proteins via OH-Radical-Rich Chemistry. Environ Technol Innov. 2026;42,104882. doi: 10.1016/j.eti.2026.104882. (IF: 7.3)
  2. Sakudo, A*, Ikuta, K. BoDV-1 Infection Is Associated with Altered Prion Protein Glycoform Maturation and Reduced ETS1-MGAT5/GnTV Pathway Activity in Rat C6 Astroglial Cells. Microorganisms. 2026;14,1759. doi.: 10.3390/microorganisms14081759. (IF: 4.7)
  3.  Sakudo A*, Furusaki K, Onishi R, Onodera T, Yoshikawa Y. A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals. Microorganisms. 2025;13(3):507. doi:10.3390/microorganisms13030507. (IF: 4.7)
  4.  Iwaya N, Sakudo A*, Kanda T, Furusaki K, Onishi R, Onodera T, YoshikawaY.　Degradation and/or Dissociation of Neurodegenerative Disease-Related Factor Amyloid-β by a Suspension Containing Calcium Hydrogen Carbonate Mesoscopic Crystals. Int J Mol Sci. 2024;25(23):12761.doi:10.3390/ijms252312761. (IF: 5.6)
  5.  Sakudo A*, Yagyu Y*. Degradation of Toxins Derived from Foodborne Pathogens by Atmospheric-Pressure Dielectric-Barrier Discharge. Int J Mol Sci. 2024;25(11):5986. doi:10.3390/ijms25115986. (IF: 5.6)
  6.  Sakudo A*. Disinfection, Sterilization, and Decontamination of Pathogens in Medicine. Microorganisms. 2023;11(4):990. doi:10.3390/microorganisms11040990. (IF: 4.7)
  7.  Sakudo A*, Yamashiro R, Onodera T. Recent Advances in Prion Inactivation by Plasma Sterilizer. Int J Mol Sci. 2022;23(18):10241. doi:10.3390/ijms231810241. (IF: 5.6)
  8. Sakudo A*, Yagyu Y. Plasma Biology 2.0. Int J Mol Sci. 2022;23(7):3684. doi: 10.3390/ijms23073684. (IF: 5.6)
  9.  Sakudo A*, Tsuji Y. Hydrogen Peroxide Gas Plasma Sterilizer Combined with Dielectric Barrier Discharge and Corona Discharge Inactivates Prions. Appl. Sci. 2021;11(20):9777. doi: 10.3390/app11209777. (IF: 2.9)
  10.  Sakudo A*, Yagyu Y. Plasma Biology. Int J Mol Sci. 2021;22(11):5441. doi: 10.3390/ijms22115441. (IF: 5.6)
  11.  Sakudo A*, Yagyu Y. Application of a Roller Conveyor Type Plasma Disinfection Device with Fungus-Contaminated Citrus Fruits. AMB Express. 2021;11(1):16. doi: 10.1186/s13568-020-01177-2. (IF: 3.9)
  12.  Sakudo A*, Anraku D, Itarashiki T. Inactivation of Prions by Low-Temperature Sterilization Technology Using Vaporized Gas Derived from a Hydrogen Peroxide-Peracetic Acid Mixture. Pathogens. 2020;10(1):24. doi: 10.3390/pathogens10010024. (IF: 3.8)
  13.  Sakudo A*, Yamashiro R, Harata C. Effect of Non-Concentrated and Concentrated Vaporized Hydrogen Peroxide on Scrapie Prions. Pathogens. 2020;9(11):947. doi: 10.3390/pathogens9110947. (IF: 3.8)
  14.  Sakudo A*, Haritani M, Furusaki K, Onishi R, Onodera T. Electrically Charged Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals as a Potential Measure to Control Xanthomonas campestris pv. campestris on Cabbage Seeds. Microorganisms. 2020;8(10):1606. doi: 10.3390/microorganisms8101606. (IF: 4.7)
  15.  Sakudo A*, Imanishi Y, Hirata A, Koga Y, Shintani H. Effect of Nitrogen Gas Plasma Generated by a Fast-Pulsed Power Supply Using a Static Induction Thyristor on Scrapie Prion. Pathogens. 2020;9(10):819. doi: 10.3390/pathogens9100819. (IF: 3.8)
  16.  Sakudo A*, Misawa T. Antibiotic-Resistant and Non-Resistant Bacteria Display Similar Susceptibility to Dielectric Barrier Discharge Plasma. Int J Mol Sci. 2020;21(17):6326. doi: 10.3390/ijms21176326. (IF: 5.6)
  17.  Sakudo A*, Iwamaru Y, Furusaki K, Haritani M, Onishi R, Imamura M, Yokoyama T, Yoshikawa Y, Onodera T. Inactivation of Scrapie Prions by the Electrically Charged Disinfectant CAC-717. Pathogens. 2020;9(7):536. doi: 10.3390/pathogens9070536. (IF: 3.8)
  18.  Sakudo A*, Yagyu Y, Onodera T. Disinfection and Sterilization Using Plasma Technology: Fundamentals and Future Perspectives for Biological Applications. Int J Mol Sci. 2019;20(20):5216. doi: 10.3390/ijms20205216. (IF: 5.6)
  19.  Sakudo A*, Yamashiro R, Haritani M, Furusaki K, Onishi R, Onodera T. Inactivation of Non-Enveloped Viruses and Bacteria by an Electrically Charged Disinfectant Containing Meso-Structure Nanoparticles via Modification of the Genome. Int J Nanomedicine. 2020;15:1387-1395. doi: 10.2147/IJN.S229880. (IF: 8.7)
  20.  Sakudo A*, Toyokawa Y, Misawa T, Imanishi Y. Degradation and detoxification of aflatoxin B-1 using nitrogen gas plasma generated by a static induction thyristor as a pulsed power supply. Food Control. 2017;73:619-626. doi: 10.1016/j.foodcont.2016.09. (IF: 7.0)
  21.  Sakudo A*. Near-Infrared Spectroscopy for Medical Applications: Current Status and Future Perspectives. Clin Chim Acta. 2016;455:181-8. doi: 10.1016/j.cca.2016.02.009.　(IF: 4.1)
  22.  Sakudo A*, Baba K, Ikuta K. Capturing and Concentrating Adenovirus Using Magnetic Anionic Nanobeads. Int J Nanomedicine. 2016;11:1847-57. doi: 10.2147/IJN.S104926. (IF: 8.7)
  23.  Sakudo A*, Onodera T. Prion Protein (PrP) Gene-Knockout Cell Lines: Insight into Functions of the PrP. Front Cell Dev Biol. 2015;2:75. doi:10.3389/fcell.2014.00075. (IF: 5.3)
  24.  Sakudo A*, Baba K, Ikuta K. Analysis of Vis-NIR Spectra Changes to Measure the Inflammatory Response in the Nasal Mucosal Region of Influenza A and B Virus-Infected Patients. J Clin Virol. 2012;55(4):334-8. doi: 10.1016/j.jcv.2012.08.015. (IF: 3.7)

*はcorresponding author

 

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